BLOOD CANCER GUIDE Blood Cancer Overview Blood Cancer Symptoms Blood Cancer Risk Factors Blood Cancer Types Blood Cancer Diagnosis Blood Cancer Stages Blood Cancer Treatment Blood Cancer Prevention Blood Cancer Symptoms Symptoms of leukemia vary depending on the type of leukemia. The most common signs and symptoms of leukaemia include:Fever;Fatigue and persistent weakness;Frequent or severe infections;Unexplained weight loss;Swelling of the lymph nodes, enlargement of the liver or spleen;Mild bleeding and rapid onset of ecchymoses;Epistaxis (recurrent nasal bleeding);Small reddish spots on the skin (petechia);Sweating abundant, especially during the night;Bone pain or bone sensitivity.